When an individual has been pushed too far, or badly treated in some way, they will quite naturally defend self without an awareness as to whether they have heard, or seen something else, that is affecting them. Over time anger builds up in the body causing physical pain in the back and legs or wrist and arms and shoulders.
We all have pangs of guilt at some time or another. It could be you have let yourself or someone else down! However, the act of not following through could be an act of self-protection while avoiding an unsavory interlude. Others may act without thought and regret it later. Still others have withdrawn, lost in paranoiac fear and pain, adding guilt to their list. This is a deep psychological issue that has arisen from early childhood, possibly while in the womb.